Lobular Carcinoma in situ (LCIS)
The cancer cells arises from the lobules of the breast ie which is the milk-producing glands ar the end of the breast ducts. In-situ means that the abnormal growth remains inside the lobule and does not spread to the surrounding breast tissues.
Those diagnosed with LCIS tend to have more than one lobule affected. More than half the cases, it’s a multifocal disease meaning multiple lobules have areas of abnormal cell growth in other quadrants of the breast. In 1/3rd of the cases, the contralateral breasts are affected.
Although it is uncommon, women diagnosed with LCIS are at a higher than average risk of developing invasive ductal or lobular breast carcinoma in her lifetime.
Treatment options
- Surgery – Lumpectomy , Mastectomy or Risk reducing mastectomy
- Hormonal therapy – Tamoxifen, Femara